disinfectant ethanol

free-slots-22,Ethanol has antimicrobial properties and is sold as a disinfectant product at optimized concentrations. Quality control of alcohol as a medical product is carried out through verification testing methods stipulated by various pharmacopoeias. As part of an agreement, the procedures for verification testing of ethanol or anhydrous ethanol in disinfectants are roughly the same in the Japanese (JP), United States (USP) and European (EP) pharmacopoeias.


ice-hockey-training-equipment,In the verification testing of ethanol and anhydrous ethanol, identification of components is carried out using Fourier Transform Infrared (FTIR) spectrophotometer. Reference spectra are compared with the spectra of the target compounds. The Japanese Pharmacopeia (JP) specifies a liquid membrane technique test, and below is a measurement example of ethanol and anhydrous ethanol using a liquid cell (KRS-5 window disk).

the infra-red absorption spectrum


volleyball-直播,Volatile impurities in ethanol are detected with a gas chromatograph (GC). Methanol, acetaldehyde, acetal, benzene, etc. are checked as impurities. An appropriate instrument configuration is required to detect the specified 2 vol ppm limit of trace benzene and obtain good separation for acetaldehyde and methanol (separation of 1.5 or higher). The testing of disinfectant ethanol is covered under the general protocol for purity testing of ethanol.


Chromatogram of Standard Solution for Ethanol for Disinfection (Overlaid Data from Three Continuous Analyses)

Chromatogram of Standard Solution for Ethanol for Disinfection (Overlaid Data from Three Continuous Analyses),tennis-grip-4

Chromatograms of Ethanol for disinfection, Sample Solution and Standard Solutions (1) – (4)

Chromatograms of Ethanol for disinfection, Sample Solution and Standard Solutions (1) – (4),soccer-shots-jersey-size-chart



The absorbance spectrum of an ethanol sample is used to test for the presence of impurities. A UV-Vis spectrophotometer is used at a wavelength range of 235-340 nm with water as a reference sample. The absorbance at three points (240 nm, 250-260 nm, 270-340nm) is checked as being below certain tolerance values (0.40, 0.30, and 0.10 respectively).,dafabet-korea

UV absorbance test



It is important to control alcohol levels in alcohol-based hand sanitizers in order to ensure constant performance. WHO recommends that hand sanitizers be prepared with an aqueous solution containing 80 % ethanol (v/v) and 75 % isopropyl alcohol (v/v). The section on ethanol for disinfection in the Japanese Pharmacopoeia states that hand sanitizers contain 76.9 ~ 81.4 % ethanol (v/v) (under conditions of 15℃).
USP and JP specify distillation and gas chromatography (GC) as methods for measuring alcohol concentration, with GC able to accurately measure ethanol concentration. A Fourier Transform Infrared (FTIR) spectrophotometer can be used to more easily measure alcohol concentration.


Chromatogram of ethanol concentration with GC,volleyball-jersey-images

IR Spectra of Brand A and B with 60% and 80% Ethanol Standards(left) 
and Brand C and Brand D with 60% and 80% IPA Standards (right)

bet365-each-way-double,FTIR allows quick and easy quantification of components included in alcohol disinfectants. The contents of ethanol and isopropyl alcohol, which are commonly used in alcohol disinfectants, were measured.

FTIR Spectroscopy

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Gas Chromatography

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Nexis GC-2030, us soccer star's premier gas chromatograph, offers a modern approach to a classic chromatographic technique. Designed with the user in mind, new innovative features, exceptional performance and high-throughput capabilities will elevate your lab to the next level.,slots-to-play-online

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